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BioMed Central | Full text | Prevalence of attention deficit/hyperactivity disorder among adults in obesity treatment

BioMed Central | Full text | Prevalence of attention deficit/hyperactivity disorder among adults in obesity treatment:

"A recent study showed the availability of striatal DRD2 receptors was decreased as a function of increasing BMI [35], supporting the idea that reward-seeking behavior plays a role in the onset or continuation of obesity. In other studies, administration of D2 agonists resulted in decreases in hyperinsulinemia associated with obesity [36], and it is known that the brain is richly supplied with insulin receptors, including the cortex and striatal areas [37], suggesting an intriguing link between insulin resistance, characteristic of obesity, and dopamine-mediated psychiatric symptoms, including ADHD. No doubt, this hypothesis and many far more refined hypotheses will be studied in coming years and will elucidate the complex neurophysiological connections hinted at by the above."
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